Disclosed are methods and sensors for detecting the presence or concentration of an analyte in a sample, preferably a sugar such as glucose, which preferably utilizes a labeled engineered protein, or fragment thereof, that is capable of binding the analyte to be detected....http://www.google.com.tw/patents/US6197534?utm_source=gb-gplus-share專利 US6197534 - Engineered proteins for analyte sensing
