The present invention relates, in general, to biosensors and, in particular, to bioelectronic sensors comprising a macromolecule immobilized on an electrode surface so that a redox cofactor that is site-specifically attached to the surface of the macromolecule is between the macromolecule and electrode...http://www.google.com.tw/patents/US6977180?utm_source=gb-gplus-share專利 US6977180 - Biosensor