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New molecular targets in Hodgkin and Reed-Sternberg cells
Frontiers
Here, we summarize current knowledge on characteristic molecular alterations in HL, as well as existing targeted therapies and potential novel treatments for...
9 months ago
Hodgkin Lymphoma: Practice Essentials, Background, Pathophysiology
Medscape
Hodgkin lymphoma (formerly, Hodgkin disease) is a potentially curable lymphoma with distinct histology, biologic behavior, and clinical...
3 weeks ago
Human leukocyte antigen (HLA) class I expression on Hodgkin¡VReed¡VSternberg cells is an EBV-independent major determinant of microenvironment composition in classic Hodgkin lymphoma
Wiley Online Library
HLA class I expression on Hodgkin¡VReed¡VSternberg cells is an EBV-independent major determinant of microenvironment composition in classic Hodgkin lymphoma.
5 months ago
terraFlow, a high-parameter analysis tool, reveals T cell exhaustion and dysfunctional cytokine production in classical Hodgkin¡¦s lymphoma
ScienceDirect.com
Immune cells express an incredible variety of proteins; by measuring combinations of these, cell types influencing disease can be precisely...
2 months ago
Reed-Sternberg cells in Hodgkin¡¦s lymphoma present features of cellular senescence
Nature
Hodgkin's Lymphoma (HL) is one of the most prevailing malignancies in young adults. Reed¡VSternberg (RS) cells in HL have distinctive large...
96 months ago
Hodgkin lymphoma (Hodgkin disease) - Symptoms and causes
Mayo Clinic
Learn how this cancer differs from other lymphomas. Find out about risk factors and treatments, such as chemotherapy, radiation and bone...
5 months ago
Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed¡VSternberg cells
PNAS
Multinucleated Reed¡VSternberg (RS) cells are pathognomonic for classical Hodgkin lymphoma (HL), and their presence is essential for diagnosis.
32 months ago
Reed¡VSternberg-Cell Leukemia and Lactic Acidosis ¡X Unusual Manifestations of Hodgkin's Disease
The New England Journal of Medicine
Reed¡VSternberg cells are the sine qua non for the diagnosis of Hodgkin's disease. Although these giant cells were pointed out by Langhans in...
177 months ago
Part I: Hodgkin's lymphoma¡Xmolecular biology of Hodgkin and Reed-Sternberg cells
The Lancet
A characteristic feature of Hodgkin and Reed-Sternberg cells in classic Hodgkin's lymphoma is the lack of expression of surface immunoglobulin (or BCR), which...
77 months ago
Chronic lymphocytic leukemia (CLL) with Reed¡VSternberg-like cells vs Classic Hodgkin lymphoma transformation of CLL: does this distinction matter? | Blood Cancer Journal
Nature
The distinction between chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with isolated Hodgkin/Reed¡VSternberg cells...
33 months ago